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Does Soy Protein Improve Heart Health?

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  1. Jenkins D, Kendall C, Faulkner D, Nguyen T, Kemp T, Marchie A et al. Assessment of the longer-term effects of a dietary portfolio of cholesterol-lowering foods in hypercholesterolemia. The American Journal of Clinical Nutrition. 2006;83(3):582-591.
  2. Krul E, Mauro L, Mukherjea R. Justification for soy protein to still have a category ‘A’ coronary heart disease risk reduction health claim. Trends in Food Science & Technology. 2014;36(1):55-58.
  3. Jenkins D. Effects of a Dietary Portfolio of Cholesterol-Lowering Foods vs Lovastatin on Serum Lipids and C-Reactive Protein. JAMA. 2003;290(4):502.
  4. Peterson K. The Dilemma With the Soy Protein Health Claim. Journal of the American Heart Association. 2020;8(13):e013202.
  5. Blanco Mejia S, Messina M, Li SS, Viguiliouk E, Chiavaroli L, Khan TA, et al. A meta-analysis of 46 studies identified by the FDA demonstrates that soy protein decreases circulating LDL and total cholesterol concentrations in adults. J Nutr. 2019;149(6):968–81.
  6. Lau J, Antman EM, Jimenez-Silva J, Kupelnick B, Mosteller F, Chalmers TC. Cumulative meta-analysis of therapeutic trials for myocardial infarction. N Engl J Med. 1992 Jul 23;327(4):248-54.
  7. Gilbert R, Salanti G, Harden M, See S. Infant sleeping position and the sudden infant death syndrome: systematic review of observational studies and historical review of recommendations from 1940 to 2002. International Journal of Epidemiology. 2005;34: 874–887.
  8. Tokede OA, Onabanjo TA, Yansane A, Gaziano JM, Djoussé L. Soya products and serum lipids: a meta-analysis of randomised controlled trials. Br J Nutr. 2015 Sep 28;114(6):831-43.
  9. de Pascual-Teresa S, Hallund J, Talbot D, Schroot J, Williams CM, Bugel S, Cassidy A. Absorption of isoflavones in humans: effects of food matrix and processing. J Nutr Biochem. 2006 Apr;17(4):257-64.
  10. Nechuta SJ, Caan BJ, Chen WY, Lu W, Chen Z, Kwan ML, Flatt SW, Zheng Y, Zheng W, Pierce JP, Shu XO. Soy food intake after diagnosis of breast cancer and survival: an in-depth analysis of combined evidence from cohort studies of US and Chinese women. Am J Clin Nutr. 2012 Jul;96(1):123-32.
  11. Inoue N, Fujiwara Y, Kato M, Funayama A, Ogawa N, Tachibana N, Kohno M, Ikeda I. Soybean β-conglycinin improves carbohydrate and lipid metabolism in Wistar rats. Biosci Biotechnol Biochem. 2015;79(9):1528-34.
  12. Chatterjee C, Gleddie S, Xiao CW. Soybean Bioactive Peptides and Their Functional Properties. Nutrients. 2018 Sep 1;10(9):1211.