« Back to Research Deepdives

Is Glycaemic Load Important for Hunger & Appetite in PCOS?

This content is restricted to members.

To view our premium content, sign up for a membership:


Register New Account

Choose your membership level

Choose Your Payment Method

‹ Back to Research Deepdives


1. Rosenbaum M, Leibel RL. Role of leptin in energy homeostasis in humans. Journal of Endocrinology. 2014;223(1):1–23.
2. Rojas J, Chávez M, Olivar L, Rojas M, Morillo J, Mejías J, et al. Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth. International Journal of Reproductive Medicine. 2014;2014:1–17.
3. Serrenho D, Santos SD, Carvalho AL. The Role of Ghrelin in Regulating Synaptic Function and Plasticity of Feeding-Associated Circuits. Frontiers in Cellular Neuroscience. 2019;13:205.
4. Japur CC, Diez-Garcia RW, de Oliveira Penaforte FR, das Graças Pena G, de Araújo LB, de Sá MFS. Insulin, ghrelin and early return of hunger in women with obesity and polycystic ovary syndrome. Physiology & Behavior. 2019;206:252–8.
5. Panidis D, Farmakiotis D, Koliakos G, Rousso D, Kourtis A, Katsikis I, et al. Comparative study of plasma ghrelin levels in women with polycystic ovary syndrome, in hyperandrogenic women and in normal controls. Human Reproduction. 2005;20(8):2127–32.
6. Geary N. Pancreatic glucagon signals postprandial satiety. Neuroscience & Biobehavioral Reviews. 1990;14(3):323–38.
7. Moran LJ, Noakes M, Clifton PM, Wittert GA, Tomlinson L, Galletly C, et al. Ghrelin and Measures of Satiety Are Altered in Polycystic Ovary Syndrome But Not Differentially Affected by Diet Composition. The Journal of Clinical Endocrinology & Metabolism. 2004;89(7):3337–44.
8. Poppitt SD, Leahy FE, Keogh GF, Wang Y, Mulvey TB, Stojkovic M, et al. Effect of high-fat meals and fatty acid saturation on postprandial levels of the hormones ghrelin and leptin in healthy men. European Journal of Clinical Nutrition. 2006;60(1):77–84.
9. Moran LJ, Luscombe-Marsh ND, Noakes M, Wittert GA, Keogh JB, Clifton PM. The Satiating Effect of Dietary Protein Is Unrelated to Postprandial Ghrelin Secretion. The Journal of Clinical Endocrinology & Metabolism. 2005;90(9):5205–11.
10. Goss AM, Chandler-Laney PC, Ovalle F, Goree LL, Azziz R, Desmond RA, et al. Effects of a eucaloric reduced-carbohydrate diet on body composition and fat distribution in women with PCOS. Metabolism. 2014;63(10):1257–64.
11. Gower BA, Chandler-Laney PC, Ovalle F, Goree LL, Azziz R, Desmond RA, et al. Favourable metabolic effects of a eucaloric lower-carbohydrate diet in women with PCOS. Clinical Endocrinology. 2013;79(4):550–7.
12. Mehrabani HH, Salehpour S, Amiri Z, Farahani SJ, Meyer BJ, Tahbaz F. Beneficial Effects of a High-Protein, Low-Glycemic-Load Hypocaloric Diet in Overweight and Obese Women with Polycystic Ovary Syndrome: A Randomized Controlled Intervention Study. J Am Coll Nutr. 2012;31(2):117-25.