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Hearty Flavonoids: Plant Bioactives and Coronary Heart Disease Risk

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1. Kromhout D, Menotti A, Bloemberg B, Aravanis C, Blackburn H, Buzina R, et al. Dietary saturated and trans fatty acids and cholesterol and 25-year mortality from coronary heart disease: the Seven Countries Study. Preventive medicine. 1995;24:308–15.
2. Croft KD. Dietary polyphenols: Antioxidants or not? Archives of Biochemistry and Biophysics. 2016;595:120–4.
3. Holst B, Williamson G. Nutrients and phytochemicals: from bioavailability to bioefficacy beyond antioxidants. Current Opinion in Biotechnology. 2008;19(2):73–82.
4. del Rio D, Rodriguez-Mateos A, Spencer JPE, Tognolini M, Borges G, Crozier A. Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases. Antioxidants & Redox Signaling. 2013;18(14):1818–92.
5. Fraga CG, Croft KD, Kennedy DO, Tomás-Barberán FA. The effects of polyphenols and other bioactives on human health. Food and Function. 2019;10(2):514–28.
6. Peterson JJ, Dwyer JT, Jacques PF, McCullough ML. Improving the estimation of flavonoid intake for study of health outcomes. Nutrition Reviews. 2015;73(8):553–76.
7. Kent K, Charlton KE, Lee S, Mond J, Russell J, Mitchell P, et al. Dietary flavonoid intake in older adults: how many days of dietary assessment are required and what is the impact of seasonality? Nutrition Journal. 2018 Dec 12;17(1):7.
8. Willet WC. Nutritional epidemiology. 3rd ed. New York: Oxford University Press; 2013.
9. Rodriguez-Mateos A, Vauzour D, Krueger CG, Shanmuganayagam D, Reed J, Calani L, et al. Bioavailability, bioactivity and impact on health of dietary flavonoids and related compounds: an update. Archives of Toxicology. 2014;88(10):1803–53.
10. Hooper L, Kay C, Abdelhamid A, Kroon PA, Cohn JS, Rimm EB, et al. Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials. The American Journal of Clinical Nutrition. 2012 Mar 1;95(3):740–51.