« Back to Research Deepdives

Does Melatonin Explain Associations Between Evening Eating and Body Fat?

This content is restricted to members.

To view our premium content, sign up for a membership:

Register New Account

Username

First Name

Last Name

Password

Password Again

Choose your membership level

Monthly Membership - €24.99 - 1 Month
Full Education Hub access: the weekly Study Deepdive, bi-monthly video Research Lectures, Exclusive Articles, and the full backcatalog of Deepdives in downloadable pdf format.
Annual Membership - €249.99 - 1 Year
Access to all the Education Hub content, at a reduced annual rate.

Discount Code - Valid - Invalid

Choose Your Payment Method

Credit / Debit Card PayPal

I agree to the privacy policy

‹ Back to Research Deepdives

References

1. Aljuraiban GS, Chan Q, Oude Griep LM, Brown IJ, Daviglus ML, Stamler J, et al. The Impact of Eating Frequency and Time of Intake on Nutrient Quality and Body Mass Index: The INTERMAP Study, a Population-Based Study. J Acad Nutr Diet. 2015;115(4):528-536.e1.
2. Kahleova H, Lloren JI, Mashchak A, Hill M, Fraser GE. Meal Frequency and Timing Are Associated with Changes in Body Mass Index in Adventist Health Study 2. J Nutr. 2017;(8):jn244749.
3. Baron KG, Reid KJ, Horn L van, Zee PC. Contribution of evening macronutrient intake to total caloric intake and body mass index. Appetite. 2013;60(1):246–51.
4. Wang JB, Patterson RE, Ang A, Emond JA, Shetty N, Arab L. Timing of energy intake during the day is associated with the risk of obesity in adults. Journal of Human Nutrition and Dietetics. 2014;27(SUPPL2):255–62.
5. Levitsky DA, Pacanowski CR. Effect of skipping breakfast on subsequent energy intake. Physiol Behav. 2013;119:9–16.
6. Sievert K, Hussain SM, Page MJ, Wang Y, Hughes HJ, Malek M, et al. Effect of breakfast on weight and energy intake: Systematic review and meta-analysis of randomised controlled trials. BMJ (Online). 2019;364:15–7.
7. Mezick EJ, Matthews KA, Hall M, Strollo PJ, Buysse DJ, Kamarck TW, et al. Influence of Race and Socioeconomic Status on Sleep: Pittsburgh SleepSCORE Project. Psychosom Med. 2008 May;70(4):410–6.
8. Eastman CI, Suh C, Tomaka VA, Crowley SJ. Circadian rhythm phase shifts and endogenous free-running circadian period differ between African-Americans and European-Americans. Sci Rep. 2015 Feb 11;5.
9. Roenneberg T, Wirz-Justice A, Merrow M. Life between clocks: Daily temporal patterns of human chronotypes. J Biol Rhythms. 2003;18(1):80–90.
10. Benloucif S, Burgess HJ, Klerman EB, Lewy AJ, Middleton B, Murphy PJ, et al. Measuring melatonin in humans. Journal of Clinical Sleep Medicine. 2008;4(1):66–9.
11. Pandi-Perumal SR, Smits M, Spence W, Srinivasan V, Cardinali DP, Lowe AD, et al. Dim light melatonin onset (DLMO): A tool for the analysis of circadian phase in human sleep and chronobiological disorders. Prog Neuropsychopharmacol Biol Psychiatry. 2007 Jan;31(1):1–11.
12. Kantermann T, Sung H, Burgess HJ. Comparing the Morningness-Eveningness Questionnaire and Munich ChronoType Questionnaire to the Dim Light Melatonin Onset. J Biol Rhythms. 2015 Oct 4;30(5):449–53.
13. McHill AW, Czeisler CA, Phillips AJK, Keating L, Barger LK, Garaulet M, et al. Caloric and macronutrient intake differ with circadian phase and between lean and overweight young adults. Nutrients. 2019;11(3):587.
14. McHill AW, Phillips AJK, Czeisler CA, Keating L, Yee K, Barger LK, et al. Later circadian timing of food intake is associated with increased body fat. American Journal of Clinical Nutrition. 2017;106(5):1213–9.
15. Flanagan A, Bechtold DA, Pot GK, Johnston JD. Chrono-nutrition: From molecular and neuronal mechanisms to human epidemiology and timed feeding patterns. J Neurochem. 2021;157(1):53–72.
16. Baron KG, Reid KJ, Wolfe LF, Attarian H, Zee PC. Phase Relationship between DLMO and Sleep Onset and the Risk of Metabolic Disease among Normal Weight and Overweight/Obese Adults. J Biol Rhythms. 2018 Feb 20;33(1):76–83.
17. Haljas K, Hakaste L, Lahti J, Isomaa B, Groop L, Tuomi T, et al. The associations of daylight and melatonin receptor 1B gene rs10830963 variant with glycemic traits: the prospective PPP-Botnia study. Ann Med. 2019 Jan 2;51(1):58–67.
18. Garaulet M, Gómez-Abellán P, Rubio-Sastre P, Madrid JA, Saxena R, Scheer FAJL. Common type 2 diabetes risk variant in MTNR1B worsens the deleterious effect of melatonin on glucose tolerance in humans. Metabolism. 2015 Dec;64(12):1650–7.
19. Garaulet M, Lopez-Minguez J, Dashti HS, Vetter C, Hernández-Martínez AM, Pérez-Ayala M, et al. Interplay of Dinner Timing and MTNR1B Type 2 Diabetes Risk Variant on Glucose Tolerance and Insulin Secretion: A Randomized Crossover Trial. Diabetes Care. 2022 Mar 1;45(3):512–9.
20. Scheer FAJL, Hilton MF, Mantzoros CS, Shea SA. Adverse metabolic and cardiovascular consequences of circadian misalignment. 2009 Mar 17;106(11):4453-8.
21. Morris CJ, Yang JN, Garcia JI, Myers S, Bozzi I, Wang W, et al. Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans. Proc Natl Acad Sci U S A. 2015;112(17):E2225–34.
22. Eckel RH, Depner CM, Perreault L, Markwald RR, Smith MR, McHill AW, et al. Morning Circadian Misalignment during Short Sleep Duration Impacts Insulin Sensitivity. Current Biology. 2015;25(22):3004–10.
23. Leproult R, Holmbäck U, van Cauter E. Circadian misalignment augments markers of insulin resistance and inflammation, independently of sleep loss. Diabetes. 2014;63(6):1860–9.