« Back to Research Deepdives

Does Choline Explain Lower Alzheimer’s Disease Risk Associated with Eggs?

This content is restricted to members.

To view our premium content, sign up for a membership:

 

Register New Account

Choose your membership level

Choose Your Payment Method

‹ Back to Research Deepdives

References

  1. Morris MC. The role of nutrition in Alzheimer’s disease: Epidemiological evidence. Eur J Neurol. 2009;16(SUPPL. 1):1–7.
  2. Wallace TC, Blusztajn JK, Caudill MA, Klatt KC, Natker E, Zeisel SH, et al. Choline: The Underconsumed and Underappreciated Essential Nutrient. Nutr Today. 2018 Nov;53(6):240–53.
  3. Morris MC. Nutritional determinants of cognitive aging and dementia. Proceedings of the Nutrition Society. 2012;71(1):1–13.
  4. Zeisel SH, Corbin KD. Choline. In: Erdman JW, MacDonald IA, Zeisel SH, editors. Present Knowledge in Nutrition. 10th ed. Oxford: Wiley-Blackwell; 2012. p. 405–19.
  5. Zeisel SH. Choline: Critical Role During Fetal Development and Dietary Requirements in Adults. Annu Rev Nutr. 2006 Aug 1;26(1):229–50.
  6. Wallace T, Fulgoni V. Usual Choline Intakes Are Associated with Egg and Protein Food Consumption in the United States. Nutrients. 2017 Aug 5;9(8):839.
  7. Ylilauri MP, Voutilainen S, Lönnroos E, Mursu J, Virtanen HE, Koskinen TT, et al. Association of dietary cholesterol and egg intakes with the risk of incident dementia or Alzheimer disease: the Kuopio Ischaemic Heart Disease Risk Factor Study. Am J Clin Nutr. 2017 Feb;105(2):476–84.
  8. Ylilauri MP, Voutilainen S, Lönnroos E, Virtanen HE, Tuomainen TP, Salonen JT, et al. Associations of dietary choline intake with risk of incident dementia and with cognitive performance: the Kuopio Ischaemic Heart Disease Risk Factor Study. Am J Clin Nutr. 2019 Dec;110(6):1416–23.
  9. Yuan J, Liu X, Liu C, Ang AF, Massaro J, Devine SA, et al. Is dietary choline intake related to dementia and Alzheimer’s disease risks? Results from the Framingham Heart Study. Am J Clin Nutr. 2022 Nov;116(5):1201–7.
  10. Blusztajn JK, Slack BE, Mellott TJ. Neuroprotective Actions of Dietary Choline. Nutrients. 2017 Jul 28;9(8).
  11. de Wilde MC, Vellas B, Girault E, Yavuz AC, Sijben JW. Lower brain and blood nutrient status in Alzheimer’s disease: Results from meta‐analyses. Alzheimer’s & Dementia: Translational Research & Clinical Interventions. 2017 Sep 26;3(3):416–31.
  12. Poly C, Massaro JM, Seshadri S, Wolf PA, Cho E, Krall E, et al. The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort. Am J Clin Nutr. 2011 Dec;94(6):1584–91.
  13. Oksman M, Iivonen H, Hogyes E, Amtul Z, Penke B, Leenders I, et al. Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice. Neurobiol Dis. 2006;23(3):563–72.
  14. Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Aggarwal N, et al. Dietary fats and the risk of incident Alzheimer disease. Arch Neurol. 2003 Feb;60(2):194–200.